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            期刊論文

            Synthesis of cluster mannosides via a Ugi four-component reaction and their inhibition against the binding of yeast mannan to concanavalin A

            管華詩 , Yingxia Li , * Xiaoru Zhang , Shidong Chu , Kunyu Yu and Huashi Guan

            Carbohydrate Research 339(2004)873-879,-0001,():

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            摘要/描述

            The Ugifour-component reaction (U-4CR) was utilized to prepare divalent and trivalent cluster mannosides with different scaolds. The glycoclusters obtained were tested for their relative inhibitory potency against the binding of yeast mannan to concanavalin A by solid-phase enzyme-linked lectin assays (ELLA) using methyl a-D-mannopyranoside as a standard. Among them, a divalent mannoside containing aromatic groups showed the strongest binding a?nity to concanavalin A.

            【免責聲明】以下全部內容由[管華詩]上傳于[2006年05月16日 00時32分39秒],版權歸原創者所有。本文僅代表作者本人觀點,與本網站無關。本網站對文中陳述、觀點判斷保持中立,不對所包含內容的準確性、可靠性或完整性提供任何明示或暗示的保證。請讀者僅作參考,并請自行承擔全部責任。

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